CONTENTS
СОДЕРЖАНИЕ
RUSSIAN
JOURNAL OF CARDIOLOGY, 2015, 8 (124)
THE NEW
EUROPEAN GUIDELINES ON NON-CARDIAC SURGERY: CARDIOVASCULAR
ASSESSMENT AND MANAGEMENT — THE
MODERN TRADITIONAL SONGS ABOUT THE MAIN?
Duplyakov D. V.
Russ J
Cardiol 2015, 8 (124): 4-5
CLINICAL
MEDICINE NEWS
Clinical medicine updates: a review of international news
Russ J
Cardiol 2015, 8
(124): 6
CLINICAL
GUIDELINES
2014 ESC/ESA
GUIDELINES ON NON-CARDIAC SURGERY: CARDIOVASCULAR ASSESSMENT
AND
MANAGEMENT
The Joint Task
Force on non-cardiac surgery: cardiovascular assessment and management
of the European Society of Cardiology (ESC) and the European
Society of Anaesthesiology (ESA)
Russ J
Cardiol 2015, 8 (124): 7–66
http://dx.doi.org/10.15829/1560-4071-2015-08-7-66
Key words: Guidelines,
Non-cardiac surgery, Pre-operative cardiac risk assessment,
Pre-operative cardiac testing, Pre-operative coronary artery
revascularization, Perioperative cardiac management, Anti-thrombotic
therapy, Beta-blockers, Valvular disease, Arrhythmias, Heart failure,
Renal disease, Pulmonary disease, Cerebrovascular disease,
Anaesthesiology, Post-operative cardiac surveillance.
2014 ESC
GUIDELINES ON THE DIAGNOSIS AND MANAGEMENT OF ACUTE PULMONARY EMBOLISM
The Task Force
for the Diagnosis and Management of Acute Pulmonary Embolism of the
European Society of Cardiology (ESC)
Russ J
Cardiol 2015, 8 (124): 67–110
http://dx.doi.org/10.15829/1560-4071-2015-08-67-110
Key words: Guidelines,
Pulmonary embolism, Venousthrombosis, Shock, Hypotension, Chest pain,
Dyspnoea, Heart failure, Diagnosis, Treatment–Anticoagulation,
Thrombolysis.
CLINIC
AND PHARMACOTHERAPY
RANDOMIZED
COMPARISON OF TWO APPROACHES TO WARFARIN DOSAGE IN
CARDIOVASCULAR HOSPITAL SECTION
Mishchenko L. N.1,
Averkov O. V.2,3, Gordeev I. G.1,
Tyulkina E. E.2,3, Pavlikova E. P.2,3,
Levchuk N. N.3, Pletnikova I. G.3
Abstract
Aim. To
compare two approaches to warfarin dosage formulation: the standard and
with the clinical algorithm.
Material and
methods. As an approach to warfarin dosage, we have
used the method that included clinical properties of the patients. Into
the group of the studied approach (intervention group), we randomized
31 person, into the standard approach group (controls) — 29 persons
with a variety of indications for vitamin K antagonists treatment.
Target diapason of International Normalized Ratio (INR) for all the
patients was 2,0 to 3,0.
Results. A
stable target INR in both groups was reached during hospitalization
just in a small part of the patients: 19,4% in intervention group and
17,2% in controls. The patients from intervention group reached stable
INR by 6,8 days in average, that is almost two times faster
than controls, who had their target INR by 12,4 day in average
(p<0,05). Part of the INR values higher than 4,0 in intervention
group was 3,6%, in control group — 18,2% (p<0,05).
Thromboembolic events (strokes, pulmonary embolism repeats) has not
developed in both groups. There was one bleeding episode in each of the
groups.
Conclusion. Opportunities
for targeting INR, not dependent on dosing regimen, are quite
restricted in inpatient settings. The patients having reached target
INR, usage of clinical algorithm of warfarin dosage helped to achieve
these values much faster than in standard approach. Prevalence of
excessive hypocoagulation while using the algorithm was lesser than in
standard group.
Russ J
Cardiol 2015, 8 (124): 111–122
http://dx.doi.org/10.15829/1560-4071-2015-08-111-122
Key words: warfarin,
warfain dose selection, INR, stable INR, clinical algorithm, standard
approach, hypocoagulation, novel anticoagulants.
1RNRMU
n. a. N. I. Pirogov, Moscow; 2PFUR, Moscow; 3CCH
№15 n. a. O. M. Filatov, Moscow, Russia.